phencyclidine-induced hallucination

phencyclidine-induced hallucination
   Phencyclidine is known under many names, including angel dust, angeldustine, and rocket fuel. The term is a truncation of the chemical name 1-(1-phenylcyclohexyl)piperidine. Abbreviated to PCP, it is classified as a dissociative anaesthetic with hallucinogenic and other neurotoxic properties. Its effects on the CNS are attributed to the joint action of NMDA receptor antagonism, dopamine receptor agonism, and the inhibition of the reuptake of dopamine, norepinephrine, serotonin, and other neurotransmitters. PCP was first synthesized in 1926 and tested as a surgical anaesthetic during the 1950s. In 1963 it was marketed as Sernyl (a name reportedly derived from serenity) and in 1967 as a veterinary anaesthetic as Sernylan, but in both cases the adverse side effects prompted the pharmaceutical company to immediately withdraw the substance from the market. As a street drug, PCP is taken orally, intravenously, rectally, vaginally, and through smoking or snorting. Its effects are dose dependent. Especially in higher doses, the effects include * hyperacusis, * auditory hallucinations (and less commonly hallucinations in any of the other sensory modalities), *metamorphopsias, feelings of weightlessness, * flashbacks, delusions, mania, *delirium, disorientation, *body schema illusions, and * out-of-body experiences. Occasionally, the use of PCP may entail a phencyclidine-induced psychotic disorder, a condition which may be indistinguishable from major psychotic disorders such as * schizophrenia. Severe intoxication may result in catatonia, a * twilight state, coma, convulsions, and death.
   Rudgley, R. (1998). The encyclopaedia of psy-choactive substances. London: Little, Brown and Company.
   Tong, T.G., Benowitz, N.L., Becker, C.E., Forni, P.J., Boerner, U. (1975). Phencyclidine poisoning. Journal ofthe American Medical Association, 234, 512-513.

Dictionary of Hallucinations. . 2010.

Look at other dictionaries:

  • Substance-induced psychosis — Classification and external resources ICD 10 F10.5 F19.5 ICD 9 …   Wikipedia

  • angel dust and hallucinations —    see phencyclidine induced hallucination …   Dictionary of Hallucinations

  • PCP and Hallucinations —    see phencyclidine induced hallucination …   Dictionary of Hallucinations

  • Ketamine — drugbox IUPAC name = 2 (2 chlorophenyl) 2 methylamino cyclohexan 1 one width = 150 CAS number = 6740 88 1 ATC prefix = N01 ATC suffix = AX03 ATC supplemental = ATC|N01|AX14 PubChem = 3821 DrugBank = APRD00493 C=13 | H=16 | Cl=1 | N=1 | O=1 smiles …   Wikipedia

  • Dextromethorphan — Not to be confused with Dexamethasone. Dextromethorphan Systematic (IUP …   Wikipedia

  • Bupropion — drugbox IUPAC name = (±) 2 ( tert butylamino) 1 (3 chlorophenyl)propan 1 one width = 200 CAS number = 34841 39 9 ChemSpiderID = 431 ATC prefix = N07 ATC suffix = BA02 PubChem = 444 smiles = CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 DrugBank = APRD00621 C =… …   Wikipedia

  • Substituted amphetamine — Optical isomers of amphetamine D amphetamine …   Wikipedia

  • Psychosis — Not to be confused with Psychopathy. For other uses, see Psychosis (disambiguation). Psychosis Classification and external resources ICD 10 F20 F29[1] ICD 9 …   Wikipedia

  • Psilocybin — Psilocybin …   Wikipedia

  • Schizophrenia — MeshName = Schizophrenia MeshNumber = F03.700.750 Schizophrenia (pron en|ˌskɪtsəˈfriːniə), from the Greek roots schizein (σχίζειν, to split ) and phrēn , phren (φρήν, φρεν , mind ) is a psychiatric diagnosis that describes a mental disorder… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.