The term dissociative comes from the Latin words dis (apart, away from each other) and associare (to gather, to unite). It translates loosely as 'a substance capable of evoking a loosening of associations'. The term dissociative is used to denote a class of the *hallucinogens characterized by the ability to reduce or block afferent signals to the conscious mind, especially those derivative of the sense organs. Some examples of dissociatives are ketamine, dextromorphan, nitrous oxide, and muscimol (derived from the mushroom Amanita muscaria). Dissociatives are believed to act via the biochemical pathway of VV-methyl D-aspartate (NMDA) receptor antagonism, and the inhibition of the action of glutamate within the CNS. It has been suggested that dissociatives evoke a pharmacologically induced state of * sensory deprivation, and a subsequently increased awareness of endogenous activity in the service of self-exploration, dreamlike activity, and hallucinatory activity. The mode of action of the primary dissociatives is thought to be similar to that of * phencyclidine (i.e. angel dust). The term dissociative is used in opposition to the terms *psychedelic and * deliriant, which refer to two additional classes of the group of hallucinogens. A person intentionally using a dissociative for the purpose of exploring the psyche may be called a *psychonaut.
   Leuner, H. (1962). Die experimentelle Psychose. Ihre Psychopharmakologie, Phänomenologie und Dynamik in Beziehung zur Person. Berlin: Springer-Verlag.
   Nichols, D.E. (2004). Hallucinogens. Pharmacology & Therapeutics, 101(2), 131-181.

Dictionary of Hallucinations. . 2010.

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  • Dissociative — Dis*so ci*a*tive, a. Tending or leading to dissociation. [1913 Webster] …   The Collaborative International Dictionary of English

  • Dissociative — See dissociation for the dissociative state in psychology. For the Australian band, see The Dissociatives. Dissociatives are a class of psychoactive drugs which are said to reduce or block signals to the conscious mind from other parts of the… …   Wikipedia

  • dissociative — ● dissociatif, dissociative adjectif Relatif à la dissociation. ● dissociatif, dissociative (expressions) adjectif Psychose dissociative, synonyme de schizophrénie. ● dissociatif, dissociative (synonymes) adjectif Relatif à …   Encyclopédie Universelle

  • dissociative — 1. adjective a) removing or separating from some association It was a lonely, dissociative time in my life, when I stayed holed up in my apartment for weeks on end. b) causing dissociation The dissociative techniques separated ammonium chloride… …   Wiktionary

  • dissociative — dis·so·cia·tive ( )dis ō s(h)ē .āt iv, shət iv adj of, relating to, or tending to produce dissociation <a dissociative chemical reaction> <hypnosis theoretically induces a dissociative state in the subject so that he or she is not aware… …   Medical dictionary

  • dissociative — /dɪˈsoʊʃətɪv/ (say di sohshuhtiv), / ˈsoʊsiətɪv/ (say sohseeuhtiv) adjective 1. of or relating to dissociation: *Hooked up to a pokie machine a gambler would almost become hypnotised and enter a dissociative state , the court heard. –aap news,… …   Australian English dictionary

  • dissociative — dissociate ► VERB 1) disconnect or separate. 2) (dissociate oneself from) declare that one is not connected with (someone or something). DERIVATIVES dissociation noun dissociative adjective. ORIGIN Latin dissociare separate …   English terms dictionary

  • dissociative — adjective see dissociation …   New Collegiate Dictionary

  • dissociative — See dissociate. * * * …   Universalium

  • dissociative — adj. pertaining to dissociation; pertaining to disunion, pertaining to separation; pertaining to the splitting of consciousness into disunited parts (Psychiatry) …   English contemporary dictionary

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